PGA & HA: Gutezimbere kwa Synergistic, Sezera kuri Stickiness, Moisturizing na Antioxidant Duet

# Intangiriro

Sodium polyglutamate (PGA)ni amazi ashonga polymer yakozwe nafermentation ya mikorobe.Irakoreshwa cyane murikwita ku ruhuibicuruzwa nakwisigabitewe nubwiza buhebuje bwiza hamwe nibikorwa byinshi.Iyi ngingo izerekana inkomoko, imiterere yimiti, ibiranga nogukoreshasodium polyglutamatemubicuruzwa byuruhu birambuye.

# Ibikoresho n'imiterere ya shimi

Sodium polyglutamateyavumbuwe bwa mbere muri natto, ibiryo gakondo byabayapani.Ubudodo bukabije cyane muri natto niPGA.Iyi ngingo ikozwe muri polimeri ikomoka kuri acide glutamic kandi yangirika kandi ikorwa na fermentation ya Bacillus subtilis.Bacillus subtilis ni imiti yemewe ya mikorobe yizewe (GRAS), isanzwe ikomoka kandi ifite umutekano kumubiri wumuntu.

Imiterere shingiro yaPGAigizwe na 5000-10000 glutamic acide molekules ya polymerizeγ-amide inkwano.Molekile irimo umubare munini wamatsinda ya polar nka hydroxyl na carboxyl, ishobora gukora hydrogène ya hydrogène imbere no hagati ya molekile, bityo igahuza amazi menshi kandi igateza imbere cyane ingaruka zayo.

#Ibiranga n'ingaruka

1. **Imikorere myiza cyane**: PGA irashobora gukurura no gufunga amazi menshi, igateza imbere cyane uruhu rwuruhu.Iyo ikoreshwa hamwesodium hyaluronate (HA), irashobora kwongerera igihe amazi ya HA, kugabanya gukomera kwayo, no gutuma uruhu rwumva neza kandi neza.

2. **Igikorwa cya Antioxydeant**: PGA ifite ibikorwa bya antioxydeant, irashobora gukuraho radicals yubusa, kandi ikarinda uruhu kwangirika kwa okiside.Ubushakashatsi bwerekanye ko PGA ifite uburemere bwa miriyoni 1,4 Da ikora neza cyane ugereranije na PGA ifite uburemere bwa miriyoni 1 Da mugushakisha DPPH yubusa.

3. **Ongera ibikubiye mubintu bisanzwe bitanga amazi (NMF) muruhu**: PGA irashobora guteza imbere igisekuru cya NMF mu ruhu, ikongerera ubushobozi bwo kuvomera uruhu, kandi ikagera ku ngaruka zintungamubiri zimbitse.

4. **Kwera no kurwanya gusaza**.

#Uburemere bwa molekulari no kubishyira mu bikorwa

Ukurikije uburemere bwa molekile, PGA irashobora kugabanywamo ubwoko butatu: uburemere bwa molekile ndende, uburemere buke bwa molekile hamwe nuburemere buke bwa molekile, buri kimwe gifite imiterere nuburyo bukoreshwa:

- **PGA-HMW (uburemere bwa molekile ndende,> 700kDa)**: kumara igihe kirekire, gukora firime itanga uruhu hejuru yuruhu, bizamura cyane ingaruka zamazi.

- **PGA-LMW (uburemere buringaniye, 70-150kDa)**: kuvomera no kwera, kunoza urumuri rwuruhu na elastique.

- **PGA-Oligo (uburemere buke bwa molekile, <10kDa)**: ibyokurya byimbitse, bigera kumurongo wibanze, biteza imbere NMF no kwinjiza intungamubiri.

#Gusaba no gukoresha ibyifuzo

PGA ikwiranye nubushuhe, kurwanya gusaza no kwera, hamwe nibisabwa hamwe0.1% kugeza 1%.Imiti igabanya ubukana bwa anti-ionic igomba gukoreshwa uko bishoboka kwose muri formula kugirango ihindure ingaruka za PGA.

#Umwanzuro

Nka biopolymer karemano, umutekano kandi ikora neza,sodium polyglutamate (PGA)yerekana imbaraga zikomeye zo gukoresha mubicuruzwa byuruhu no kwisiga.Ibintu byiza cyane bitanga amazi, ibikorwa bya antioxydeant hamwe ninyungu nyinshi kubuzima bwuruhu bituma iba ikintu cyingenzi mubicuruzwa byita ku ruhu bigezweho.Hamwe no kongera ubushakashatsi no guteza imbere ikoranabuhanga,PGAbiteganijwe ko izagira uruhare runini mubice byinshi no kuzana udushya niterambere mu ikoranabuhanga ryita ku ruhu.