HA PRO® ACETYLATED SODIUM HYALURONATE
Ibicuruzwa
HA PRO® ACETYLATED SODIUM HYALURONATE Ishusho Yerekanwe

HA PRO® ACETYLATED SODIUM HYALURONATE

Ibisobanuro bigufi:

Sodium acetylated hyaluronate muguhuza igice cya hydroxyl ya hydroxyl ya sodium hyaluronate mumatsinda ya acetyl binyuze mumiti ya chimique, bityo ikaba ifite hydrophilicity na lipophilicity, ishobora gukinisha amazi abiri, antioxydeant, anti-inflammatory, gusana inzitizi ya keratine nibindi. imikorere yibinyabuzima.Irashobora gutuma umwuma n'ubukonje bw'uruhu byumva neza, bigatuma uruhu rworoha kandi rworoshye, kandi rushobora gukoreshwa cyane mubicuruzwa byo kwisiga bya buri munsi.

Kumenyekanisha ibicuruzwa

Imiterere yumubiri na chimique: Kugaragara ni ifu yera cyangwa yoroheje yumuhondo, byoroshye gushonga mumazi.

Ibiranga ibicuruzwa ni nkibi bikurikira

1. Ubushuhe buhebuje

2. Gukata radicals yubusa, anti-oxyde na anti-gusaza

Kurwanya inflammatory

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1. Ubushuhe buhebuje

Umuti wuzuye wa ammonium sulfate ukoreshwa mukubungabunga ubushuhe bugereranije kuri 81%.Menya itandukaniro ryuburemere hagati yifu ya HA na AcHA yashyizwe kuri 1h-8h, igenzura ryiza glycerine, iranga kugumana ububobere bwayo;nkuko bigaragara ku gishushanyo 1, aho AcHA ari nimero 2: Ikizamini cyerekana ko muri 1h, AcHA ifite hejuru cyane ya glycerine no kugumana ubuhehere bwa HA isanzwe;muri 1-8h, kugumana ubushuhe bwintangarugero zose zangirika igihe, ariko kugumana ubuhehere bwa AcHA bwari bukiri hejuru kurenza ubundi bugenzuzi.

HA1: uburemere buke bwa sodium hyaluronate;HA2: acetylated sodium hyaluronate;

HA3: uburemere busanzwe bwa molekuline sodium hyaluronate;

Igishushanyo1: Ikigereranyo cyo kugumana ubushuhe bwa buri cyitegererezo kuri buri mwanya

2. Gukata radicals yubusa, anti-oxyde na anti-gusaza

Mu gisubizo cya Ethanol, molekile 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH) irashobora gukora azote ihamye irimo azote yubusa.Ifite imbaraga zikomeye kuri 517nm, kandi scavenger yubusa irashobora guhuza hamwe na electron imwe kugirango ibuze igisubizo.Iri hame rikoreshwa mukugereranya umubare wubushobozi bwa antioxydeant yibinyabuzima bikora.Binyuze mu kizamini cy’ingaruka ku gisekuru cya DPPH yubusa, herekanwa ko ugereranije nitsinda rishinzwe kugenzura, acetylated HA ifite ubushobozi bwo gusibanganya DPPH yubusa, kandi ikarenza uburemere busanzwe bwa molekile yubusa.

HA1: uburemere buke bwa sodium hyaluronate;

AcHA: acetylated sodium hyaluronate

Igishushanyo 2: Igipimo cyubusa cya sodium acetylated hyaluronate

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3.Anti-inflammatory gusana

Ubushobozi bwo kurwanya inflammatory bwagenwe nuburyo bukoreshwa na immunosorbent ya enzyme.Ubushakashatsi bwerekanye ko 1µg / mL lipopolysaccharide (LPS) ishobora gukangurira ingirabuzimafatizo za HaCaT kubyara ibintu bitera indwara, kandi ubushobozi bwibikoresho fatizo byo kubuza urwego rwibintu byatewe na ELISA.Nkuko bigaragara ku gishushanyo cya 3, ugereranije na acide isanzwe ya hyaluronike, imvugo ya 1L-1α mu itsinda rya acide acide hyaluronic aside yagabanutse ku buryo bugaragara, kandi ikizamini cyerekanye ko AcHA ifite ubushobozi bukomeye bwo guhagarika ibintu bitera umuriro.

HA2: acetylated sodium hyaluronate;

HA3: uburemere busanzwe bwa sodium hyaluronate:

Igishushanyo 3: Kugaragaza 1L-1α mu ngirabuzimafatizo zitandukanye

Ibisobanuro ku bicuruzwa

Izina RY'IGICURUZWA Acetylated sodium hyaluronate
Ibisobanuro ku bicuruzwa Ifu yera cyangwa umuhondo cyangwa granule
Inyungu zibicuruzwa Ubushuhe buhebuje, AcHA ifite imiterere ihanitse cyane kuruta glycerine na HA isanzwe;

Gukata radicals yubusa, anti-okiside no kurwanya gusaza, AcHA ifite ubushobozi bwo gusiba DPPH yubusa, kandi irenze uburemere busanzwe bwa molekuline yubusa radical scavenging urwego ;

Kubuza gutwika no gusana, AcHA ifite ubushobozi bugaragara bwo kubuza ibintu gutwika ugereranije na aside isanzwe ya hyaluronike ;

Ibisobanuro ku bicuruzwa Kumenyekanisha A.Ibikoresho bitagabanijwe neza
BA ibara ryibara ribaho hamwe na acide ya uronic
C. Itanga reaction (a) ya sodium
Ibirimo Acetyl

23.0-29.0%

pH

5.0-7.0

Gutakaza kumisha

≤10.0%

Ibisigisigi kuri Ignition

11.0% -16.0%

Kwinjira imbere

0.50-2.80dL / g

Icyuma kiremereye (nka Pb)

≤20ppm

Arsenic

≤2.0ppm

Ibirimo azote

2.0-3.0%

Indwara ya bagiteri

≤100CFU / g

Ibishushanyo & Umusemburo

≤30CFU / g

Staphylococcus aureus

Ibibi / g

Pseudomonas aeruginosa

Ibibi / g

Ububiko Ubike mu kirere, ubushyuhe bwicyumba.
Gupakira

Ukurikije ibyo umukiriya asabwa

Ubuzima bwa Shelf Imyaka ibiri (gupakira)

 

Amabwiriza yo gukoresha

Icyifuzo gisabwa: 0.01% -0.1%;

Ikoreshwa: gushonga byoroshye mumazi, birashobora kongerwaho muburyo bwamazi;uruhu rwumva ruruhura kandi ntirufashe

Urutonde rwo gusaba: rushyirwa mubintu byo kwisiga nka essence, mask yo mumaso, cream, amavuta yo kwisiga, nibindi.

Kubaza

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